| Question | Quick answer |
|---|---|
| What is it? | Increased intestinal permeability |
| The hallmark sign | Gut symptoms plus skin, joints, mood or energy |
| Often mistaken for | A diagnosis in its own right, or a digestive issue alone |
| How it’s investigated | GI-MAP microbiome testing |
Your gut lining is meant to be selective, absorbing nutrients while keeping larger particles out of the bloodstream. Increased intestinal permeability means those junctions have loosened, so material crosses that normally would not, and the immune system responds to it. That immune response is what produces symptoms well beyond digestion. See the wider picture on gut health.
It is a mechanism, not a diagnosis. That distinction matters: permeability is something that happens because of an underlying driver, so the useful question is always what caused it rather than treating the permeability alone.
Common drivers include gut infections and dysbiosis, chronic stress, alcohol, some medications, and long-running inflammation. Those overlap heavily with IBS and with bacterial overgrowth and candida.
A diagnosis in its own right. it is a mechanism. Treating permeability without finding the driver usually means the symptoms return.
Only a digestive problem. because the immune system is involved, skin, joints, mood and energy are often affected as much as the gut.
Something a supplement alone fixes. gut-lining support can help, but only once whatever is damaging the lining has been identified and addressed.
GI-MAP microbiome testing looks at the drivers directly: dysbiosis, pathogens, inflammatory and immune markers from the gut itself, interpreted by a naturopath alongside your history rather than read as a list of results. Where the picture suggests it, we add other functional testing. In-clinic or Telehealth, Australia-wide.
One sign alone is rarely the whole story. It’s the cluster, and the pattern over time, that points to a treatable cause.
See your GP for blood in your stool, unexplained weight loss, persistent vomiting, fever, or severe ongoing abdominal pain. Coeliac disease and inflammatory bowel disease need excluding before symptoms are attributed to permeability.
Commonly bloating and digestive discomfort, reacting to a growing range of foods, fatigue and brain fog, skin flare-ups such as eczema or acne, low-grade joint aches, and getting sick often. Because the immune system is involved, symptoms usually extend beyond digestion.
Increased intestinal permeability is a real, measurable mechanism and is well described in the research. It is not a standalone diagnosis, which is why good care looks for what is driving the permeability rather than treating the permeability by itself.
Common drivers include gut infections and dysbiosis, bacterial overgrowth, chronic stress, alcohol, some medications, and long-running inflammation. Identifying which driver applies is what makes a plan effective.
We test the drivers rather than the label. GI-MAP microbiome testing assesses dysbiosis, pathogens and inflammatory and immune markers from a stool sample, and your practitioner interprets it alongside your symptom history.
Supporting the gut lining works best once you know what is wearing it down. Let’s test the drivers and build the plan from there.
Short on time? Get fast, personalised advice with a free 15-minute consult from our Naturopath or Nutritionist. No appointment needed. Just drop in or give us a call.